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A variant that combines the identified deltas and omicrons.Dogs sniff out viruses with high accuracy

Computer-generated representation of COVID-19 virions via Felipe Esquivel Reed / CC BY-SA

The following is a summary of recent studies on coronavirus disease 2019 (COVID-19). They require further research to support the findings and include studies that have not yet been certified by peer review.

“Deltacron” where the genes for Delta and Omicron were found
A hybrid version of the coronavirus (called “Deltacron”), which combines genes from Delta and Omicron variants, has been identified in at least 17 patients in the United States and Europe, the researchers said.

Philippe Colson of IHU Mediterranee Infection in Marseille, France, posted Tuesday, saying it’s too early to know if Deltacron infections are very contagious or cause serious illness, as the number of confirmed cases is so small. He said he was the lead author of the report. medRxiv Prior to peer review.

His team described three French patients infected with a combined version of the delta variant “body” with a peaplomer from the Omicron variant.

Two other unrelated Deltacron infections have been identified in the United States, according to an unpublished report by genetics research firm Helix submitted to medRxiv and seen by Reuters. On the Virus Research Bulletin Board, other teams have reported 12 more Deltacron infections in Europe since January. All of these are accompanied by Omicron spikes and delta bodies.

Genetic recombination of human coronavirus is known to occur when two mutants infect the same host cell.

“During the SARS-CoV-2 pandemic, two or more subspecies co-circulated in the same geographic region during the same period … this created an opportunity for recombination between these two subspecies.” Colson said his team designed a PCR test that “can quickly test positive samples for the presence of this … virus.”

Dogs sniff out coronavirus with high accuracy
New studies add evidence that trained dogs can help screen crowds to identify people infected with the coronavirus.

At two regional screening centers in Paris, 335 volunteers who underwent traditional PCR tests also provided sweat samples. Overall, 78 symptomatic and 31 asymptomatic patients were positive for PCR.

According to a report posted on Tuesday, dogs were 97% accurate in detecting infected patients and 100% accurate in detecting infections in asymptomatic patients, given the odor of sweat samples. medRxiv Prior to peer review. It was also 91% accurate in identifying uninfected volunteers and 94% accurate in excluding infections in asymptomatic people.

“Dog testing is non-invasive and provides fast and reliable results,” the authors say. “Further research will focus on direct detection by dogs to evaluate detection dogs for mass pre-testing at airports, ports, train stations, cultural activities, or sporting events.”

Future concerns may lie in today’s patients

Many coronavirus particles inside infected individuals are likely to contain some mutant particles that may prove to be early examples of significant mutations, new findings suggest. Suggests.

After a thorough analysis of viral particles from 10 people with alpha variant-induced infections in Spain in April 2021, researchers identified mutant particles that resembled the Omicron variant. This was not officially identified until seven months later.They also found a characteristic mutation in the shape of the Delta and Jota, according to a report released Tuesday. Clinical research journal..

Although identifying the predominant mutations in individual patients may be sufficient for diagnostic purposes, the “ultra-deep” gene sequencing used in this study may evolve into mutations of concern to scientists. Researchers said it could help track mutations in SARS-CoV-2 particles.

“The virus that replicates in each infected patient is actually a slightly different mixture of SARS-CoV-2 viruses, and these different viruses make up different proportions of the complete’ensemble’,” he said. Celia Perales, co-author of the Madrid Autonomous University, said. She said that minority mutations in one infected person could prevail over someone else by chance or because of the selective benefits associated with the presence or absence of drugs, vaccines, or other factors. — — Nancy Rapid / Reuters

A variant that combines the identified deltas and omicrons.Dogs sniff out viruses with high accuracy A variant that combines the identified deltas and omicrons.Dogs sniff out viruses with high accuracy

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