According to researchers, infrared therapy may help people with dementia.
A pilot study led by Dr. Paul Chazot of Durham University in the United Kingdom and Dr. Gordon Dougal of Maculume Ltd showed improvement in memory, motor function, and processing skills of healthy people with normal intellectual function with age.
As a result, researchers also benefit people with dementia from transcranial photobiomodulation therapy (PBM-T), which uses a specially designed helmet worn by patients to self-deliver infrared radiation to the brain. Said there is a possibility.
They emphasized that further research on the use and efficacy of treatments is needed, but the discovery of their pilots is promising.
The study is published in the journal Photobiomodulation, photomedicine and laser surgery.
The study found that 14 healthy people over the age of 45 from the United Kingdom received PBM-T twice daily for 6 minutes at a wavelength of 1068 nanometers over a four-week period. This was done with a control group of 13 members using a dummy PBM-T helmet.
Scientists conducted a series of memory, language, and motor skills tests on participants in both groups before and after the treatment period to see what improvements in function were achieved.
Researchers found that healthy people who received PBM-T were in the control placebo group.
Participants reported no adverse effects caused by the treatment.
Dr. Paul Chazot, Research Co-Leader, Faculty of Life Sciences, Durham University, said: Consistent and short infrared rays.
“This is a pilot study and needs more research, but there are promising signs that treatments involving infrared may also be beneficial for people with dementia, which is certainly worth investigating. In addition, we and our US collaborators recently also published a new independent clinical study that provides first evidence of a profound and rapid improvement in dementia memory capacity.
“Infrared light of a particular wavelength has been shown to help reduce nerve cell damage, amyloid loading, and decreased blood flow in the brain that are common in people with dementia, so it’s a game-changing multiplayer. Can it be used as a modal form of treatment?
“This could offer a new disease modification strategy for dementia that has the potential to alleviate many of the serious problems faced by people with dementia and reduce the burden on caregivers.”
The PBM-T helmet was invented by Dr. Dougal, a practitioner based in Durham, England.
It works by irradiating the skull with infrared light at a wavelength of 1,060 to 1,080 nanometers that supplies 1,368 J of energy to the skull every 6-minute treatment cycle from 14 fan-cooled LED light arrays focused by the skull. To do.
It stimulates mitochondria, which produce most of the chemical energy needed to stimulate the cell’s biochemical reactions. This raises the level of an organic compound called adenosine triphosphate (ATP), which is significantly reduced in people with dementia. It promotes the process of living cells and provides energy to help repair nerve cells.
Researchers say the treatment can also increase nitric oxide levels and thus increase blood flow in the brain by improving the flexibility of the membranes that line blood vessels. This opens blood vessels and allows more oxygen to reach the deep white matter of the brain.
The helmet is easy for the patient to wear, making it easy to treat at home. Researchers believe that it may also be beneficial for other disorders such as Parkinson’s disease, traumatic brain injury, and motor neuron disease. The cost of purchasing each helmet is approximately £ 7,250.
Dr. Gordon Dougal, Co-Research Leader of Maculume Ltd, said: Laboratory studies investigating the mechanism of action of PBM-T1068 have shown that this therapeutic tool may help dying brain cells to regenerate into functioning units.
“More research is needed to fully understand the mechanism of action.”
This pilot study follows a 20-year study by Dr. Chazot to identify, develop, and validate infrared rays of specific wavelengths used to treat dementia through a series of in vitro and in vivo preclinical studies.
These studies show for the first time that certain wavelengths of PBM-T improved memory capacity and reduced beta-amyloid. It usually plays an essential role in nerve growth and repair, but it can increase and destroy nerves in later years.Leads to loss of cell thinking and memory Alzheimer’s disease Disease-A mouse model of Alzheimer’s disease.
The latest findings follow a recently published individual pilot Alzheimer’s disease clinical study involving Dr. Chazot and Dr. Dougal.
Published in the journal Cureus When Aging and illness, And these findings, led by Dr. Jason Fung (University of Texas A & M), show that PBM-T1068 (also known as transcranial near-infrared (tNIR) treatment) has similar profoundness in both male and female conditions. With mild to moderate dementia, which suggested that it had a rapid positive effect.
For example, in the Cureus study, 39 patients received 6 minutes of PBM-T twice daily for 8 weeks with a control group of 17 patients using dummy helmets.
The Mini-Mental State Examination (MMSE) showed a 20% improvement in treated women, while a 19% improvement (4.8 MMSE unit increase) in men from just 8 weeks of treatment. This was compared to a 6.5% improvement in women and a 5.9% improvement in men, respectively, in the control group.
After a few weeks, participants reported having more energy, uplifting, and less anxiety, along with better physical and mental involvement in daily activities. Improvements in mood were also pointed out by caregivers.
Again, no adverse effects from participants or caregivers related to treatment during or after treatment have been reported. Cureus study.
Case study – “I was more relaxed and had more energy”
Grandmother Tracy Sloan began using an infrared therapy helmet to improve her memory.
After wearing the helmet for a few weeks, she said she noticed an improvement in remembering a brief message. I would have had to write it down or forgot it before.
She also noticed that her sleep and mood improved.
Tracy, 56, a general practitioner in Peterlee, Durham, is generally healthy and has no diagnosed condition that could affect her memory. She was introduced to a cure by Dr. Dagal.
She wore a helmet in the morning and evening for three months, six minutes each time.
Tracy, who has two daughters and two grandchildren, said:
“I didn’t know if that would make a difference, but to be honest, I think it made a difference.
“After a few weeks, I noticed that my sleep patterns improved, I felt relaxed, and I had more energy.
“I’m not a moody person, but my youngest daughter said I wasn’t moody, and the manager at the time laughed and said the treatment should work because I didn’t have to write things down. “
According to Tracy, the helmet is easy to use and is worn while watching TV in the evening.
“My kids will look at me and say,’What’s on my head?’ But if this helps me in any way, I thought it was worth it,” she says. I did.
“It was very light to wear and I could plug it in while I was wearing it.”
Tracy believes that after the trial period, he stopped using the treatment and his memory deteriorated after he stopped.
She added: “It definitely helped me and I want to use it again.
“If people can afford something like this and it makes your quality of life much better, I’ll definitely try it.”
Reference: “Effects of transcranial near-infrared light 1068 nm on memory capacity of healthy elderly individuals: pilot study” October 18, 2021 Photobiomodulation, photomedicine and laser surgery..
DOI: 10.1089 / pho.2020.4956
Infrared therapy may help people with dementia
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