Researchers Picture COVID-19 Severity and Results in South Carolina

Percentage of symptoms in South Carolina COVID-19 patients (n = 280177). Abbreviations: COVID-19, Coronavirus Disease 2019. Credit: DOI: 10.1093 / ofid / ofab428

The first state-wide population-based study of COVID-19 symptoms and clinical outcomes showed disparities between different groups, especially by race / ethnicity and geographic location (local and urban). Older people, men and blacks are more likely to experience hospitalization and death, and rural residents face a particularly high risk of death. Compared to Caucasian individuals, Hispanic / Latin American patients were more likely to have moderate / severe symptoms, while Asian patients were not.

“These findings unfortunately support the fact that social determinants of rural settlements and racial / ethnic health continue to be predictors of adverse health effects in COVID-19 patients. “. Health PromotionXiaoming Li, Professor of Education and Behavior, SmartState is the Chair of Clinical Translational Research at the Health Care Quality Center and Co-Senior Research Fellow at the UofSC Big Data Health Science Center. Li led the UofSC team, which conducted the study in collaboration with the South Carolina Department of Health and Environment Management.

Since the pandemic began in early 2020, South Carolina has experienced some of the highest infection and mortality rates in the United States. Mainly rural states with severe medical shortages hold some of the worst rankings and trends in the country. As of October 19, 2021, there were nearly 890,000 cases and more than 13,000 deaths associated with COVID-19, and only 49% of the eligible population (aged 12+) were fully vaccinated. I have been inoculated.

According to the author, previous studies on the severity of the disease caused by COVID-19 give an incomplete picture of the true trends occurring throughout South Carolina and the United States. The drawback of these studies is that patient samples limited to inpatients or identified from a single medical system (patients with asymptomatic / mild illness, or living outside of that particular medical system). (Excluding patients), small sample sizes collected in a short period of time, and / or cases not hospitalized.

“Based on existing studies, most people (about 40-45%) infected with SARS-CoV-2 are asymptomatic or experience mild to moderate symptoms, with about 14 cases. % And 5% go from severe to severe, respectively, “said Xueying Yang, assistant professor of health promotion, education, and behavioral research who was the lead author of this paper. “However, due to the limitations of these studies, the data we currently have on the severity and outcome of the disease of COVID-19 do not necessarily represent the full range of the disease.”

In its first study in the United States, researchers analyzed data from more than 280,000 COVID-19 cases supplied by various South Carolina medical facilities between March and December 2020. This data contains information about socio-demographic characteristics. Symptom / illness severity, hospitalization and mortality.

Was announced in Open Forum Infectious Diseases, Their analysis revealed statistics that could be generalized to the state’s population. For example, researchers found that more than 5% of COVID-19 patients were hospitalized and nearly 2% died. Some of their most notable discoveries focused on rural and urban disparities that were not well studied and / or rarely reported in previous studies.

The team found that people living in rural areas were at increased risk of death from COVID-19, but were not hospitalized at a higher rate than residents in urban areas. One explanation indicates low access to medical services, including preventative therapies (such as monoclonal antibodies) and critical care units in severe / advanced cases. The authors also note that rural areas have a high incidence of chronic diseases associated with the adverse consequences of COVID-19 (hypertension, obesity, diabetes, etc.). Other findings are in close agreement with the results of previous studies, but provide additional insights and a more complete picture of the status of COVID-19.

“This study shows that unified state policies and actions may not explain the specific vulnerabilities faced by rural communities and may increase inequality,” Li said. Mr. says. “National programs require coordinated efforts to improve their social and economic status in these areas.”

People over the age of 40 with type 1 diabetes and COVID-19 are more likely to be hospitalized

For more information:
Xueying Yang et al, Demographic Disparities in Clinical Outcomes of COVID-19: Data from a State-Wide Cohort in South Carolina, Open Forum Infectious Diseases (2021). DOI: 10.1093 / ofid / ofab428

Quote: Researchers obtained from on October 27, 2021 South Carolina (October 27, 2021) Draw a picture of the severity and results of COVID-19

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