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Thyroid problems associated with increased risk of dementia-ScienceDaily

Elderly people with hypothyroidism (also known as hypothyroidism) may be at increased risk of developing dementia, according to a study published online on July 6, 2022. Neurology®, American Academy of Neurology Medical Journal. The risk of developing dementia was even higher for people whose thyroid condition required thyroid hormone replacement drugs.

Hypothyroidism occurs when the thyroid gland does not produce enough thyroid hormone. This can slow down metabolism. Symptoms include fatigue, weight gain, and poor circulation.

“In some cases, thyroid disorders are associated with treatment-reversible symptoms of dementia,” said Chien-Hsiang Weng, MD, MPH, a research author at Brown University in Providence, Rhode Island. .. “More research is needed to confirm these findings, but people see thyroid problems as a potential risk factor for dementia and treatment that can prevent or delay irreversible cognitive decline. You need to be aware. “

In this study, researchers examined the health records of 7,843 newly diagnosed people with dementia in Taiwan and compared them to the same number of people without dementia. Their average age was 75 years. Researchers examined people with a history of either hypothyroidism or hyperthyroidism. Hyperthyroidism, also known as hyperthyroidism, is when the thyroid gland produces excess hormones. This can increase metabolism. Symptoms include unintentional weight loss, rapid or arrhythmia, nervousness or anxiety.

A total of 102 had hypothyroidism and 133 had hyperthyroidism.

Researchers have not found a link between hyperthyroidism and dementia.

Of those with dementia, 68 (0.9%) had hypothyroidism, compared with 34 (0.4%) without dementia. Researchers have adjusted for other factors that may affect the risk of dementia, such as gender, age, high blood pressure, and diabetes, and people over the age of 65 with hypothyroidism are more than people of the same age. Also found to be 80% more likely to develop dementia. There is no thyroid problem. For people under the age of 65, a history of hypothyroidism was not associated with an increased risk of dementia.

When researchers looked only at people who took medication for hypothyroidism, they found that they were three times more likely to develop dementia than those who did not. “One explanation for this may be that these people are more likely to experience greater symptoms from hypothyroidism that needed treatment,” Weng said.

Weng said observational studies have not proven that hypothyroidism is the cause of dementia. Only associations are displayed.

The limitation of the study was that researchers were unable to include information about how severe hypothyroidism was for participants.

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