What is Sweet Syndrome? Is Sweet Syndrome Infectious?

Overview Overview Overview

Sweet syndrome mainly causes fever with a painful skin rash on the face, neck and arms. Sweet syndrome is an unknown skin condition called acute febrile neutrophil dermatitis. However, the exact cause of Sweet syndrome is unknown. However, it can be caused by medications, illnesses, and infections. In addition, Sweet Syndrome can occur with certain types of cancer. Sweet syndrome as a disease is not contagious, is not a type of skin cancer, nor is it hereditary. Sweet syndromes are generally treated with corticosteroids.

What are the signs and symptoms of Sweet Syndrome?

Signs and symptoms of sweet syndrome may disappear within a few days of treatment, but may recur. Some of the common symptoms of Sweet Syndrome are:

  • heat
  • A ridge that grows easily in size and spreads over painful clusters.
  • Small painful red ridges on the back, neck, face and arms.
  • Muscle and joint pain
  • Skin and mouth lesions
  • Discoloration of the skin
  • I feel sick.

Therefore, if you witness any of the above symptoms or develop a painful red rash that grows rapidly in size, you should immediately contact your doctor to decide on a treatment plan.

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How Does Sweet Syndrome Affect the Skin?

The most common change in the skin with Sweet Syndrome is the development of red to purple soft skin spots or lumps. They, small or large, can come together to form a large lump. In addition, pustules and blisters can be seen, and a rash can appear at the site of the injury, leading to infection.

Sweet syndrome affects the skin as well as other internal organs and tissues. The other parts of the body affected by Sweet Syndrome are bones and joints. In addition, the ears, eyes and mouth are also affected by Sweet Syndrome. The red ridge may extend from the outer ear to the eardrum. The eyes may swell due to redness and inflammation. Sweet syndrome can cause pain in the tongue, inside the cheeks, and gums. It has also been observed that Sweet Syndrome can cause inflammation of the internal organs of the chest and abdomen.

What Causes Sweet Syndrome?

The exact cause of Sweet syndrome is unknown. However, this condition may be associated with some types of cancer, such as blood cancer, breast cancer, and colon cancer. In addition, a drug reaction that stimulates white blood cell production in the body can cause Sweet Syndrome.

How are sweet syndromes classified?

Doctors classify Sweet Syndrome into three categories:

  • A sweet syndrome associated with malignant tumors. It is found in certain types of cancer, such as acute myeloid leukemia.
  • Classic sweet syndrome. Sweet syndrome can also occur in other medical conditions such as upper respiratory tract infections, gastrointestinal infections, and pregnancy.
  • Drug-induced sweet syndrome. Sweet syndrome can be caused by several drugs such as sulfamethoxazole, trimethoprim, granulocyte colony stimulating factor (G-CSF), and NSAIDs.

What are the risk factors associated with Sweet Syndrome?

Sweet syndrome is a rare disease, but several factors increase the risk of being diagnosed with the disease.

  • age. Sweet syndrome can occur at any age. However, the disease mainly affects people between the ages of 30 and 60.
  • Sex. It has been observed that women are more likely to be diagnosed with Sweet Syndrome than men.
  • cancer. Sweet syndrome may be associated with cancers such as leukemia, breast cancer, and colon cancer.
  • pregnancy. Some women may be diagnosed with Sweet Syndrome during pregnancy.
  • Drug sensitivity. Sweet syndrome can also result from susceptibility to several drugs, such as azathioprine and some non-steroidal anti-inflammatory drugs.

How is Sweet Syndrome Diagnosed?

A dermatologist will diagnose a sweet syndrome by a physical examination of your skin. However, to better diagnose and evaluate Sweet Syndrome, health care professionals prescribe some tests, such as:

  • Skin biopsy. The doctor removes small pieces of affected tissue for examination.
  • Blood test. Blood samples are sent to the laboratory to check the white blood cell count and other blood parameters.

How is Sweet Syndrome treated?

Sweet syndrome can go away without treatment, but medications can speed up the recovery process. The most common medications prescribed for the treatment of Sweet Syndrome are:

  • Oral treatment. Oral corticosteroids are effective in treating Sweet Syndrome. However, long-term use of these tablets can cause side effects such as insomnia, bone weakness, and weight gain.
    • Steroid tablets such as prednisolone are effective in treating Sweet Syndrome.
    • Immunosuppressants such as cyclosporine may help treat Sweet Syndrome.
    • Other drugs such as Dappswan, Potassium Iodide, Colchicine, and Indomethacin can help treat Sweet Syndrome.
  • injection. A small amount of corticosteroid can be injected into the lesion.
  • Ointment and cream. These are applied to the affected area of ​​the skin, but they can thin the skin.

Health care professionals will prescribe the above medications for several weeks to avoid recurrence. Some alternatives that doctors can prescribe when long-term corticosteroid intake is a problem:


If you have had a fever for the past few days, have bumpy rashes all over your body, spread rapidly, and these rashes hurt, you should see a doctor. Sweet syndrome is not contagious, nor is it a type of skin cancer or heredity. It may disappear without medicine. However, taking the drug speeds up the recovery process. Sweet syndrome has been observed to recover even after treatment. Some of the medications prescribed by healthcare professionals to treat Sweet Syndrome are steroids, immunosuppressants, and other medications. Some of these drugs can have certain side effects, and a dermatologist may advise regular blood tests to monitor the prescribed treatment.

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