Science & Technology

Wolbachia-infected mosquitoes with stimulating dengue epidemic: study

DDistribute infected mosquito eggs Wolbachia Bacteria dramatically reduced cases of dengue and hospitalization in the intervention area compared to the non-intervention area, the researchers reported today (10 June). New England Journal of MedicineUnder research Wolbachia As a potential public health tool to combat dengue Go back For over a decade, this is the first randomized trial of a strategy.

“It provides a gold standard of evidence such as: Wolbachia It’s a very effective intervention for dengue, “said Oliver Brady, a dengue expert at the London School of Economics and Tropical Medicine who was not involved in the study. Atlantic“It could revolutionize mosquito control.”

Wolbachia Present in many arthropod species Manipulate Breeding in its host to ensure that it becomes widespread in the population. In laboratory experiments, once you get into a mosquito, Wolbachia It competes with the virus that causes dengue fever for resources and prevents the virus from colonizing the host. (This principle also applies to other viruses, such as: Zika.. )

Wolbachia Not naturally present in dengue vectors Aedes aegyptiMore than a decade ago, researchers developed a way to introduce bacteria into mosquitoes in a way that would be transmitted from females to offspring. next, Wolbachia Unveiled by non-profit World Mosquito Program (WMP) researchers who have the potential to combat dengue in the real world Aedes aegypti In 2011, it was infected with bacteria in northern Australia and several other countries.Number of dengue infections in Australian release areas drop Up to 96% after adoption, results from other sites were also promising, but the work was observational and Wolbachia Caused a reduction.

In the current study, WMP randomly assigned 24 geographic areas in Yogyakarta, Indonesia to receive or act as a control for infected mosquito eggs. Researchers enrolled hot participants who visited clinics in treated and untreated areas, and 9.4% of those who lived in the control area had dengue, whereas they lived in the egg-releasing zone. It was found that only 2.3% of people with fever had dengue fever. disease.Researchers reported this 77% reduction Incidence of dengue fever in last year’s press release. In a new treatise, they also report a reduction in hospitalization due to dengue in the treated area.

“That’s really big,” said research co-authors Monash University in Melbourne and Cameron Simmons at WMP. Science. “It’s the weight of hospitalization … It really expands the medical system.”

by Atlantic, WMP is currently active in 11 countries, with 7 million people Wolbachia-Infected Aedes aegyptiThe organization aims to protect at least 500 million people by 2030.

Wolbachia-infected mosquitoes with stimulating dengue epidemic: study Wolbachia-infected mosquitoes with stimulating dengue epidemic: study

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