Young transplant patients respond better to the COVID vaccine

“Almost three-quarters of the pediatric transplant recipients we investigated showed a positive and protective antibody response after two doses of the Pfizer / BioNTech Messenger RNA (mRNA) vaccine. Dose.” Said. Douglas Mogul, an associate professor of pediatrics at Johns Hopkins University School of Medicine, said.

This study, published in the American Journal of Transplantation, investigated 57 pediatric solid organ transplant recipients vaccinated with the Pfizer / BioNTech vaccine. The median age was 14 years (range 12-18 years).

Positive antibody levels against SARS-CoV-2 were found in 73% of 45 children with samples available after two vaccinations. Of the 30 individuals whose antibody titers were measured after both the first and second shots, 17% showed a negative titer after both, 33% showed a negative titer and became positive, and 47% It showed a positive titer throughout. One patient (3%) who had a positive titer after one dose and negative after the second dose.

Researchers report no organ rejection or other unexpected adverse events among the study participants. Two patients were tested positive for SARS-CoV-2 infection during the study.

“Further research is needed to show whether two doses provide clinical protection, otherwise a third dose will serve to boost the immune system of those who are unable to respond after the second dose. We need to show our role, “added Qin.

Source: IANS

Back to top button